S. V. Mir Ahmed Ali was born on 15 July 1902 in Madras, British India. He was born into a family whose paternal ancestors were descendants from the Fourth Holy Imam Ali ibn al-Husayn Zayn al-'Abidin, who called themselves Sajjadis. Originally from Hejaz, they migrated to India through Iran and settled down at Bijapur. His great-grandfather Mir Abdul Ali Sajjadi served as a commander in the Mughal Army and earned the distinction with the title Vafakhani for his loyalty to the crown. Thereafter, the members of his family became popular as Sajjadi Vafakhani.

Early years, education and public life
Mir Ahmed Ali received primary education from his maternal uncle Mr. Mir Jaffer Hussain Peer and later matriculation at Harris High School, Madras. After that he joined the Govt. Mohamadan College in clerical services. During his service he obtained the title of Munshi Fazil, B.O.L Degree and qualified himself with M.A in Arabic and Persian. He was then absorbed in the same college as Asst. Professor and later on he got B.T and M.Ed. degree from Madras University. The interest in Arabic and Persian made him pursue a Diploma in higher proficiency in those languages. It was at this time when he founded The Hussainy Trust (formerly known as Madarasa-e-Hussainy and Yateemkhana) in 1943.

Mir Ahmed Ali traveled extensively after taking voluntary retirement from Govt. Mohamadan College. In the mid-fifties in his travels through India and abroad, he devoted his entire life to the upliftment of the orphans and destitute children. The trust expanded and grew, bringing in much required funds to serve many and still following-up on the work initiated by him. It continued the hard work and love towards orphans and the destitute. He served as the president of The Hussainy Trust until his death.